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Aspis Biopharmaceutical was an early-stage biotechnology startup co-founded by researchers from the University of Southern California (USC) Keck School of Medicine. The company was established to develop disintegrin-based diagnostic and therapeutic solutions derived from snake venom. Its lead candidate, Vicrostatin (VCN), is a recombinant chimeric disintegrin designed to target multiple integrins (including alpha-V beta-3, alpha-V beta-5, and alpha-5 beta-1) to inhibit tumor angiogenesis, metastasis, and progression. The technology was later transitioned to Applied Integrin Sciences, which has since ceased operations.
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