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AstralBio develops novel antibody therapeutics for cardiometabolic and immune-mediated diseases. Its lead programs target myostatin and Activin E to address obesity and muscle metabolism. In early 2025, it licensed a long-acting anti-myostatin antibody (IBIO-600) to iBio for obesity/muscle wasting. In April 2025, the collaboration expanded to include an anti–Activin E antibody for fat-selective weight loss. Both assets are preclinical; no clinical results reported yet.
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