Company intelligence / Profile preview

Atalanta Therapeutics

Boston, Massachusetts, United Statesatalantatx.com ↗
Ownership
Private
Employees
~75
Development stage
Preclinical
01

Overview

Atalanta Therapeutics has developed a proprietary di-siRNA platform that enables potent, durable gene silencing throughout the brain and spinal cord. The company has demonstrated preclinical proof-of-concept for its lead programs, including sustained silencing of the huntingtin gene in animal models. IND submissions are planned for their first two programs—targeting Huntington's disease and KCNT1-related epilepsy—in late 2025. No human clinical results have been reported yet as of May 2025.[6][7]

Therapeutic areas
Neurology
Modalities
RNA interference (RNAi)Divalent small interfering RNA (di-siRNA)
Industry
Biotech
02

Drug pipeline

9 assets

ATL-101

1

8 more assets in the full pipeline.

03

Partnerships

Genentech/Roche – strategic collaboration on undisclosed CNS targets using di-siRNA technology[5][8].Biogen – previous partnership on Huntington's program; now unwinding with full rights reverting to Atalanta[8].

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