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Audion Therapeutics

Amsterdam, Netherlandsaudiontherapeutics.com ↗

Ownership: Private
Development stage: Phase 2

Overview

Audion Therapeutics has completed a Phase I/IIa trial of LY3056480, an intratympanically administered gamma-secretase inhibitor for sensorineural hearing loss. The Phase I trial with 15 patients confirmed safety and tolerability of the highest dose (250 micrograms). Some patients showed improvements in speech understanding in noisy environments, with benefits continuing during the 12-month follow-up period. The company has advanced to a multi-center Phase II efficacy study with 40 adult patients with mild to moderate SNHL in the UK, Germany, and Greece.[5][7][8]

Therapeutic areas: Neurology
Modalities: Small molecules (gamma-secretase inhibitor)
Industry: Biotech

Drug pipeline

1 asset

LY3056480

Discontinued

Partnerships

REGAIN consortium (international consortium of 7 partners)

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