Company intelligence / Profile preview

Aurealis Therapeutics

Zug, Zug, Switzerlandaurealistherapeutics.com ↗
Ownership
Private
Development stage
Phase 2
01

Overview

Aurealis Therapeutics has completed a Phase I trial and recently finished patient treatment in a Phase II trial of its lead product AUP‑16 for non-healing diabetic foot ulcers, with positive safety and efficacy data reported. The company has also published peer-reviewed results from its clinical studies. Its oncology candidate AUP‑55 targeting ovarian cancer and peritoneal carcinomatosis is in preclinical development. The company’s unique platform uses live genetically engineered lactic acid bacteria to deliver multiple therapeutic proteins directly at the disease site, acting as nanoscale drug bioreactors.[1][3][5][6]

Therapeutic areas
ImmunologyOncologyEndocrinologyCardiovascular
Modalities
Live biotherapeutic products (genetically modified lactic acid bacteria)Cell therapy (bacterial vector-based)Gene therapy
Industry
Biotech
02

Drug pipeline

5 assets

AUP-16

2

4 more assets in the full pipeline.

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03

Partnerships

Licensing agreement with Chinese partner for AUP‑16 in China ($139M deal plus royalties); seeking further global/regional licensing partners.[3]Sponsorship of EWMA Diabetic Foot Committee.[1]

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