Company intelligence / Profile preview
Aurealis Therapeutics
Zug, Zug, Switzerlandaurealistherapeutics.com ↗
- Ownership
- Private
- Development stage
- Phase 2
01
Overview
Aurealis Therapeutics has completed a Phase I trial and recently finished patient treatment in a Phase II trial of its lead product AUP‑16 for non-healing diabetic foot ulcers, with positive safety and efficacy data reported. The company has also published peer-reviewed results from its clinical studies. Its oncology candidate AUP‑55 targeting ovarian cancer and peritoneal carcinomatosis is in preclinical development. The company’s unique platform uses live genetically engineered lactic acid bacteria to deliver multiple therapeutic proteins directly at the disease site, acting as nanoscale drug bioreactors.[1][3][5][6]
- Therapeutic areas
- ImmunologyOncologyEndocrinologyCardiovascular
- Modalities
- Live biotherapeutic products (genetically modified lactic acid bacteria)Cell therapy (bacterial vector-based)Gene therapy
- Industry
- Biotech
02
Drug pipeline
5 assets4 more assets in the full pipeline.
03
Partnerships
Licensing agreement with Chinese partner for AUP‑16 in China ($139M deal plus royalties); seeking further global/regional licensing partners.[3]Sponsorship of EWMA Diabetic Foot Committee.[1]
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