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ABS is developing first-in-class, highly specific monoclonal antibodies and antisense oligonucleotides that target the soluble interleukin-7 receptor (sIL7R), aiming to restore immune homeostasis in genetically defined subpopulations with autoimmune diseases resistant to current therapies. Clinical results have not yet been reported as the programs are preclinical, but the approach is supported by strong genetic and biochemical rationale.[1][3][5][14]
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