Company intelligence / Profile preview

Avadel Pharmaceuticals

Dublin, Irelandavadel.com ↗
Ownership
Public · AVDL
Employees
~194
Development stage
Commercial
01

Overview

Avadel’s lead product LUMRYZ™—a once-at-bedtime extended-release formulation of sodium oxybate—received FDA approval in May 2023 for the treatment of cataplexy or excessive daytime sleepiness in adults with narcolepsy. It was granted seven years’ orphan drug exclusivity due to clinical superiority over existing twice-nightly oxybates. As of Q1 2024, >1,700 patients had initiated therapy; pediatric and idiopathic hypersomnia trials are ongoing/pending.[6][7][8]

Therapeutic areas
OtherNeurology
Modalities
Small molecules (notably sodium oxybate)[6][9]
Industry
Biotech
02

Drug pipeline

4 assets

AV001

Approved

3 more assets in the full pipeline.

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03

Partnerships

RTW Investments – royalty acquisition agreement ($75M) [March 2023][7].Clinical collaborations include Stanford University on some studies/trials.[9]

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