Company intelligence / Profile preview

Avalo Therapeutics

Rockville, Maryland, United Statesannualreports.com ↗
Ownership
Public · AVTX
Employees
~23
Development stage
Phase 2
01

Overview

Avalo’s lead program is AVTX-009, an anti–IL‑1β monoclonal antibody in Phase 2 for hidradenitis suppurativa. The company recently pivoted its pipeline to focus on this asset after acquiring AlmataBio and deprioritizing previous assets such as quisovalimab and a BTLA agonist fusion protein. Previous programs included AVTX‑002 for non-eosinophilic asthma and COVID‑19 ARDS; however, recent trials did not meet primary endpoints but showed positive trends in biomarker-defined subpopulations[10][7]. The company has secured significant funding to advance the current lead program through key clinical milestones.

Therapeutic areas
PulmonologyImmunologyDermatologyRare DiseasesInfectious Diseases
Modalities
monoclonal antibodies (mAbs)fusion proteins
Industry
Biotech
02

Drug pipeline

14 assets

rislenemdaz

2

13 more assets in the full pipeline.

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03

Partnerships

No major pharmaceutical partnerships disclosed post-pipeline pivot. Recent investors include Commodore Capital, TCGX, BVF Partners, Deep Track Capital, OrbiMed, Petrichor and RA Capital Management[7].

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