Axem Neurotechnology

Axem Neurotechnology has developed a proprietary system combining a wearable headband device and software to guide and monitor at-home neurorehabilitation for stroke patients. The technology uses functional near-infrared spectroscopy to measure brain activity during movement. Clinical trials have demonstrated feasibility and safety of the system in improving motor recovery post-stroke; one trial was completed with positive feasibility results and another early phase trial focused on home-based use remains ongoing or recently completed. "Axem's proprietary system consists of software guided rehabilitation paired with a mobile functional neuroimaging device to promote brain activity patterns that drive recovery...established proof of concept..." "The device uses functional near-infrared spectroscopy (fNIRS) to measure changes in brain activity during movement." "Randomized open label trial analyzing the safety and feasibility of coupling the Axem Home prototype device with exercise to improve motor recovery following a stroke." The company has met with FDA regarding regulatory pathways. No commercial product yet; seeking seed-stage investment as of last update. Two clinical trials registered: NCT05258591 ("fNIRS-PROMOTE-Recovery"): Early Phase 1/Unknown status—portable method for post-stroke rehab using fNIRS BCI. NCT05016193 ("Axem Home study"): Completed Phase 1—safety/feasibility study for independent use by stroke survivors.