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Axentis was a Swiss clinical-stage biotechnology company focused on developing inhaled liposomal anti-infectives for chronic respiratory infections. The company utilized its proprietary Fluidosome platform to encapsulate antibiotics like tobramycin, aiming to enhance drug penetration into pulmonary biofilms and reduce systemic toxicity. Its lead program was targeted at treating Pseudomonas aeruginosa infections in patients with cystic fibrosis and non-cystic fibrosis bronchiectasis. In 2013, the company was acquired by Aradigm Corporation to complement their existing inhaled liposomal ciprofloxacin programs.
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