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Axovan was a Swiss biopharmaceutical company focused on the discovery and development of novel small molecule drugs targeting G protein-coupled receptors (GPCRs). The company's lead program was clazosentan (formerly AXV-03), a selective endothelin receptor antagonist designed to prevent cerebral vasospasm following subarachnoid hemorrhage. Founded by a team of former Roche scientists, Axovan leveraged its expertise in GPCR biology to build a pipeline of candidates for cardiovascular and neurological disorders. The company was acquired by Actelion in 2003 to strengthen Actelion's specialty pipeline in the hospital market.
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