B.Twelve

B.Twelve is a Danish biotechnology company specializing in the development of targeted therapeutic and diagnostic agents using the natural Vitamin B12 (cobalamin) transport system. The company leverages the high expression of the transcobalamin receptor (CD320) in rapidly dividing cells, such as cancer cells and activated macrophages, to deliver payloads with high specificity. Their platform focuses on B12-conjugates that can carry various cargos, including imaging agents and cytotoxic drugs, to improve efficacy and reduce systemic toxicity. Founded by experts in cobalamin metabolism, B.Twelve aims to address unmet needs in oncology and inflammatory disorders through its proprietary delivery technology.