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Baker Brothers Advisors is a leading, highly influential hedge fund and investment management firm specializing in biotechnology and life sciences. Founded by Felix and Julian Baker in 2000, the New York-based firm manages over $9 billion as of Q1 2025, with historical AUM exceeding $20 billion at times. The fund is known for its concentrated bets on high-potential biotech companies and has generated some of the industry's largest returns through long-term holdings such as Seagen (acquired by Pfizer). Their approach involves deep scientific diligence, active board participation, and close relationships with portfolio company management teams[1][2][3][6].
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