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Belhaven Biopharma has developed Nasdepi®, a dry powder intranasal epinephrine product for the emergency treatment of anaphylaxis. Phase 1 clinical data show Nasdepi® achieves comparable or superior pharmacokinetics to standard intramuscular injection, with rapid absorption and good tolerability. The product offers advantages in shelf stability, heat resistance, ease of use, and accessibility compared to autoinjectors. The company has completed dose-confirmation studies supporting commercial dose selection and plans a pivotal biocomparability study as part of its NDA-enabling program.
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