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BerGenBio ASA

Ownership: Private
Employees: ~50
Development stage: Phase 2

Overview

BerGenBio developed first-in-class selective AXL inhibitors for aggressive cancers and severe respiratory diseases. Its lead asset, bemcentinib, showed promise in early clinical trials for NSCLC and AML but failed to demonstrate sufficient efficacy in recent phase II studies targeting STK11-mutant NSCLC. As of early 2025, the company has discontinued its key remaining study with bemcentinib and announced exploration of strategic alternatives following disappointing results.[10] The company also has antibody-based assets available for licensing or outlicensed.

Therapeutic areas: OncologyInfectious Diseases
Modalities: Small molecules (e.g., bemcentinib)Monoclonal antibodies (e.g., tilvestamab)Antibody-drug conjugates (outlicensed technology)
Industry: Biotech

Drug pipeline

3 assets

bemcentinib

2 more assets in the full pipeline.

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Partnerships

University of Texas Health Science Center at San Antonio / Mays Cancer Center [5][8]Swedish Orphan Biovitrum AB (“Sobi”) – collaboration on pacritinib combo trial [5][8]ADC Therapeutics – outlicensing of antibody technology for ADCT‑601 [7]

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