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BioAegis Therapeutics

North Brunswick, New Jersey, United Statesbioaegistherapeutics.com ↗
Ownership
Private
Development stage
Phase 2
01

Overview

BioAegis Therapeutics’ lead asset—recombinant human plasma gelsolin—is in a global Phase 2 trial for moderate-to-severe ARDS. The study involves over 600 patients across multiple countries and aims to demonstrate efficacy in improving survival without organ failure at Day 28. The company’s approach has shown promise as a non-immunosuppressive anti-inflammatory therapy that restores innate immune balance and may address high unmet needs in severe inflammatory conditions. Early results have supported safety and mechanistic rationale; pivotal efficacy data are pending from the ongoing trial.[6][8]

Therapeutic areas
ImmunologyPulmonologyNeurologyInfectious Diseases
Modalities
Recombinant proteins (notably recombinant human plasma gelsolin, rhu-pGSN)[1][4][10]
Industry
Biotech
02

Drug pipeline

3 assets

Recombinant human plasma gelsolin

2

2 more assets in the full pipeline.

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03

Partnerships

BARDA – $20 million contract to support ARDS clinical development of rhu-pGSN [6][10]

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