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Bionica International is a medical technology and biotechnology company focused on the development and commercialization of Pulsatile Intravenous Insulin Therapy (PIVIT), also known as Metabolic Activation Therapy (MAT). The company's proprietary technology utilizes specialized infusion pumps to deliver insulin in precise, high-concentration pulses that mimic the natural physiological secretion of the pancreas. This method is designed to "turn on" the liver's metabolic processes, improving glucose utilization and addressing the underlying metabolic defects in patients with Type 1 and Type 2 diabetes. Bionica's therapy aims to not only control blood sugar but also to prevent or reverse chronic diabetic complications such as neuropathy, retinopathy, and nephropathy. The company has also investigated the application of its pulsatile delivery platform for other conditions, including infectious diseases like COVID-19 and various metabolic disorders. Headquartered in Sacramento, California, Bionica has a long history in the manufacturing of advanced infusion systems and has partnered with clinical providers to deliver its specialized treatments globally.
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