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BioSpecifics developed and commercialized injectable collagenase clostridium histolyticum (marketed as XIAFLEX in the US and Xiapex in Europe) for Dupuytren’s contracture and Peyronie’s disease. The company also advanced CCH into late-stage development for cellulite ("Qwo") and explored additional indications such as adhesive capsulitis and various benign tumors. Positive clinical results were reported across multiple indications prior to acquisition by Endo International.
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