BIOTRH

BIOTRH s.r.o. is a Czech medical device company specializing in the development and manufacturing of injectable hydrophilic gels for aesthetic and reconstructive surgery. The company's flagship product line, Los Deline (formerly marketed as Aquafilling), consists of sterile, non-absorbable gels used for soft tissue augmentation in the face, breasts, and buttocks. BIOTRH operates out of Prague and utilizes manufacturing facilities in collaboration with Biomedica spol. s.r.o. While the company has established a global presence in the aesthetic medicine market, its products have recently been subject to field safety notices and regulatory scrutiny regarding long-term complications and certificate withdrawals in several European markets.