Company intelligence / Profile preview
Bitterroot Bio
Palo Alto, California, United Statesbrbio.com ↗
- Ownership
- Private
- Employees
- ~50
- Development stage
- Phase 1
01
Overview
Bitterroot Bio has initiated a Phase 1 clinical trial of its lead candidate BRB‑002, targeting the CD47/SIRPα pathway for atherosclerosis and vascular inflammation. Preclinical data demonstrated efficacy and safety in animal models. The company is now evaluating safety and tolerability in healthy volunteers, with plans to advance to proof-of-concept studies in patients with cardiovascular disease[7].
- Therapeutic areas
- Cardiovascular
- Modalities
- Protein therapiesImmune cell therapy[6]
- Industry
- Biotech
02
Drug pipeline
2 assets1 more asset in the full pipeline.
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Partnerships
No major pharmaceutical partnerships disclosed as of May 2025. Clinical trial partnership with Nucleus Network for Australian studies.[7]Investors include ARCH Venture Partners, Deerfield Management, GV, Koch Disruptive Technologies, Alexandria Venture Investments.[2][8]
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