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BJT‑778, a fully human IgG1 monoclonal antibody targeting HBsAg, has received EMA PRIME designation based on promising early Phase 1/2 data in HDV. Additional programs include small molecule HBsAg inhibitors and TLR9 agonists, all aiming to achieve functional cure rates for chronic HBV and HDV infections. Clinical development is ongoing with robust investor support and recent major funding rounds.
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