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Blueprint Medicines has developed and commercialized avapritinib for multiple forms of systemic mastocytosis and certain gastrointestinal stromal tumors. The company also advanced elenestinib and BLU‑808 into clinical development targeting additional allergic/inflammatory conditions. Its pipeline includes both approved drugs and investigational therapies at various stages. Clinical results have demonstrated efficacy in rare hematologic malignancies and solid tumors driven by specific genetic alterations.
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