Company intelligence / Profile preview

Bolden Therapeutics

Providence, Rhode Island, United Statesboldentherapeutics.com ↗
Ownership
Private
Development stage
Other
01

Overview

Bolden Therapeutics has demonstrated proof-of-concept in proprietary mouse models showing increased neurogenesis and improved hippocampal-dependent memory by modulating a novel signaling pathway with exon-skipping antisense oligonucleotides. The company has received NIH/NIA SBIR/STTR grants to advance these candidates toward clinical development for Alzheimer’s disease and related CNS disorders. Human clinical trials have not yet begun.

Therapeutic areas
NeurologyCardiovascular
Modalities
Antisense oligonucleotide
Industry
Biotech
02

Drug pipeline

2 assets

bdnf antisense oligonucleotide

Preclinical

1 more asset in the full pipeline.

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03

Partnerships

Biogen (“Golden Ticket” incubator sponsorship at LabCentral/Kendall Square Cambridge MA lab space support)

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