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Bolt Biotherapeutics is conducting a Phase 1 trial for BDC-3042, a first-in-class Dectin-2 agonist antibody that repolarizes immune cells to destroy tumors. The Boltbody™ ISAC platform has generated multiple product candidates, some in collaboration, targeting tumor antigens and leveraging innate and adaptive immune responses[1][2][3]. Most available data is early stage with limited clinical results disclosed.
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