Company intelligence / Profile preview
BrickBio
Woburn/Boston area, Massachusetts, United Statesbrickbio.com ↗
- Ownership
- Private
- Employees
- ~4
- Development stage
- Preclinical
01
Overview
BrickBio has demonstrated strong preclinical results with its ADCs. Its lead candidate BRKB‑28 showed potent efficacy against breast and gastric cancers in vitro without affecting healthy cells. The company recently reported a fivefold increase in the therapeutic window of a PBD-based ADC targeting B7-H3/CD276 with complete tumor eradication in animal models.[9][10] No clinical-stage assets are publicly disclosed as of May 2025.
- Therapeutic areas
- OncologyNeurology
- Modalities
- Antibody-drug conjugates (ADCs)Bispecific antibody conjugatesNovel protein scaffoldsProtein origami therapeuticsSynthetic virology (AAV modification)
- Industry
- Biotech
02
Drug pipeline
8 assets7 more assets in the full pipeline.
03
Partnerships
Abcam – partnership to incorporate conjugation-ready sites into recombinant antibodies across Abcam’s portfolio[4].Large pharmaceutical company for co-development of ADCs [6].*(Additional pharma partnerships implied but not all partners named.)*
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