Company intelligence / Profile preview
Brii Biosciences
Beijing, Beijing, Chinadirectory.ncbiotech.org ↗
- Ownership
- Public · 2137.HK
- Development stage
- Commercial
01
Overview
Brii Biosciences has advanced its core hepatitis B functional cure program with multiple ongoing Phase 2b trials. Key assets include BRII-179—a recombinant protein-based immunotherapeutic vaccine—BRII-835/elebsiran—an siRNA targeting HBV—and BRII-877/tobevibart—a broadly neutralizing monoclonal antibody. Recent data show promising immune responses and antiviral effects in chronic HBV patients. The company has received Breakthrough Therapy Designations for all three main assets in China. Other pipeline programs in CNS disorders and HIV have been deprioritized as the company focuses on late-stage development of curative regimens for chronic hepatitis B
- Therapeutic areas
- PsychiatryInfectious Diseases
- Modalities
- Small interfering RNA (siRNA)Recombinant protein-based immunotherapeutics (therapeutic vaccines)Monoclonal antibodies (mAbs)Long-acting injectables
- Industry
- Biotech
02
Drug pipeline
10 assets9 more assets in the full pipeline.
Request access →03
Partnerships
Vir Biotechnology Inc .(co-development/licensing of elebsiran ,tobevibart )VBI Vaccines Inc .(licensing of BRII –179 )
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