Broadcaster

Broadcaster is a pre-clinical stage biotechnology company co-founded by physician-scientist Siddhartha Mukherjee to develop a novel class of engineered cell therapies known as "Broadcaster cells." The company's platform focuses on engineering specific immune cells, particularly B cells, to act as localized delivery vehicles that "broadcast" therapeutic payloads directly within the tumor microenvironment. By leveraging the natural homing abilities and longevity of these cells, Broadcaster aims to deliver potent agents like cytokines or antibodies in a site-specific manner, thereby reducing systemic toxicity and overcoming the immunosuppressive barriers of solid tumors. This approach represents a significant evolution in cell therapy, moving beyond direct cell-mediated killing to localized, multi-functional protein secretion. The company is headquartered in New York and is backed by prominent venture capital firms including 8VC.