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Calcilytix Therapeutics

San Francisco, California, United Statescalcilytix.com ↗

Ownership: Private
Development stage: Other

Overview

Calcilytix Therapeutics is a clinical-stage biopharmaceutical company focused on developing therapies for rare disorders of calcium and phosphate metabolism. The company's lead program, encaleret, is an investigational small molecule calcilytic designed to antagonize the calcium-sensing receptor (CaSR). By inhibiting CaSR, encaleret aims to restore normal parathyroid hormone secretion and normalize blood calcium levels in patients with Autosomal Dominant Hypocalcemia Type 1 (ADH1). Originally established as a subsidiary of BridgeBio Pharma, Calcilytix was acquired by Alexion, AstraZeneca Rare Disease, in 2022 to expand their late-stage rare disease endocrinology portfolio.

Therapeutic areas: Endocrinology
Modalities: Small molecule
Industry: Biotech

Drug pipeline

1 asset

encaleret

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