Company intelligence / Profile preview
Calico Life Sciences
South San Francisco, California, United Statescalicolabs.com ↗
- Ownership
- Private
- Employees
- ~365
- Development stage
- Phase 1
01
Overview
Calico Life Sciences focuses on understanding the fundamental biology that controls human aging and translating these discoveries into interventions targeting age-related diseases. The company has a growing pipeline spanning preclinical to early clinical stages, with notable progress in rare neurodegenerative disease therapeutics such as Fosigotifator for Vanishing White Matter Disease. Its approach combines advanced computation, interdisciplinary research, and extensive collaborations with industry leaders like AbbVie. While the company has not yet produced late-stage or commercialized therapies as of early/mid‑2025, it remains a leading innovator in longevity science.[1][3]
- Therapeutic areas
- OtherOncologyNeurology
- Modalities
- Small molecules[3]Potentially biologics (inferred from broad R&D focus)[2]Advanced computing and systems biology approaches[1][2]
- Industry
- Biotech
02
Drug pipeline
5 assets4 more assets in the full pipeline.
03
Partnerships
AbbVie — major R&D collaboration focused on age-related disease therapeutics ($billions committed over a decade) [3]Denali Therapeutics — ALS drug development partnership [3]Terray Therapeutics — small-molecule discovery collaboration [3]
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