California Medical Innovations Institute

California Medical Innovations Institute (CalMI2) is a non-profit biomedical research institute based in San Diego, California, that functions as an "innovation engine" for clinical translation. Founded in 2014 by Dr. Ghassan Kassab, the institute focuses on addressing significant healthcare challenges in cardiovascular, gastrointestinal, and metabolic diseases. CalMI2 utilizes a multidisciplinary approach combining in vivo studies, computational modeling, and bench testing to advance the development of diagnostics and therapeutics. The institute offers specialized research facilities, including AAALAC-accredited surgical suites and advanced imaging technologies, to support collaborations with clinicians and industry partners. Its work spans from basic research to the development of innovative medical devices, such as the Fecobionics system for mapping neuromuscular function.