Calvert Research Institute

Calvert Research Institute (CRI) is a non-profit research organization dedicated to accelerating the development of new therapies through translational medicine and drug repurposing. Based in Cary, North Carolina, the institute leverages a collaborative model, partnering with academia, industry, and patient advocacy groups to identify novel uses for existing drug compounds. CRI's primary mission is to address unmet medical needs in rare diseases and oncology by streamlining the path from laboratory discovery to clinical application. By utilizing data-driven approaches and preclinical validation, the institute aims to reduce the time and financial barriers associated with traditional drug development. Their work specifically targets the "Valley of Death," the challenging transition period between basic research and clinical trials. Through these efforts, CRI seeks to deliver innovative treatments to patients more efficiently and cost-effectively.