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CambriaTech Holding was a biotechnology holding company that operated primarily through its subsidiary, Cambria Pharmaceuticals. The company focused on discovering small molecule drugs for neurodegenerative diseases, with a particular emphasis on Amyotrophic Lateral Sclerosis (ALS) and Parkinson's disease. Its core technology utilized a proprietary yeast-based screening platform to identify compounds that stabilize proteins prone to misfolding, such as SOD1. In 2011, the company entered into a major strategic collaboration with Biogen Idec to develop its SOD1 stabilizer program for ALS. Despite its innovative approach to protein aggregation, the company has since ceased active operations and entered liquidation.
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