Canadian Immunodeficiency Research Collaborative

The Canadian Immunodeficiency Research Collaborative (CIRC) is a national non-profit organization dedicated to advancing the care of patients with primary immunodeficiency (PI) and related autoinflammatory disorders. Based in Toronto, the collaborative facilitates multicenter clinical research and manages comprehensive national patient registries to track outcomes and improve treatment standards across Canada. CIRC brings together a network of leading Canadian immunologists and researchers to address unmet needs in the diagnosis and management of rare immunological conditions like Hereditary Angioedema (HAE). The organization is also instrumental in developing clinical practice guidelines and providing medical education to healthcare professionals. By fostering partnerships between academia, industry, and patient groups, CIRC accelerates the translation of scientific discoveries into improved clinical care for the immunology community.