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CanZx Biotherapeutics (operating as CanCure, LLC) is a biotechnology company focused on developing a new generation of cancer immunotherapies. The company's lead asset, CuraB-10 (also known as CB-10 or SYB-010), is a first-in-class monoclonal antibody designed to target soluble MIC (sMIC), a ligand that tumors shed to evade the immune system. By neutralizing sMIC and stabilizing tumor-bound MIC, CanZx aims to restore the innate and adaptive immune response against various solid tumors, including prostate cancer and melanoma. The company has established strategic partnerships with Samyang Biopharm and CHA Biotech to advance its pipeline and explore combination therapies. Beyond oncology, CanZx is exploring the application of its technology in infectious and autoimmune diseases.
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