Captisol

Captisol, a subsidiary of Ligand Pharmaceuticals, is a drug delivery technology company centered around its patented sulfobutylether beta-cyclodextrin (SBE-CD) platform. The technology is designed to improve the solubility, stability, and bioavailability of active pharmaceutical ingredients, particularly those that are poorly water-soluble. Captisol is used in numerous FDA-approved products, including Veklury (remdesivir), Kyprolis, and Nexterone. The company operates primarily through a licensing and supply model, partnering with global pharmaceutical firms to enhance their drug formulations. Its manufacturing capabilities ensure high-purity, GMP-grade material for clinical and commercial use worldwide.