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Cara Therapeutics, Inc.

Stamford, Connecticut, United Statescaratherapeutics.gcs-web.com ↗

Ownership: Public · CARA
Development stage: Commercial

Overview

The company's lead product difelikefalin (KORSUVA) has shown mixed results in clinical trials. In June 2022, they announced positive topline results from the KOMFORT Phase 2 trial of oral difelikefalin for pruritus. However, in June 2024, they announced that oral difelikefalin did not demonstrate meaningful clinical benefit compared to placebo in the KOURAGE-1 Part A study for Notalgia Paresthetica, leading to discontinuation of that program.

Therapeutic areas: GastroenterologyNeurologyDermatologyNephrology
Modalities: PeptidesKappa opioid receptor agonists
Industry: Biotech

Drug pipeline

2 assets

difelikefalin

Approved

1 more asset in the full pipeline.

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Partnerships

HealthCare Royalty ($40 million financing agreement)

Financials

Market cap: $8.1M
Total revenue: $0
Enterprise value: $-7.5M

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