Company intelligence / Profile preview
Carisma Therapeutics
- Ownership
- Public · CARM
- Employees
- ~40
- Development stage
- Other
Overview
Carisma's liver fibrosis program (CT-2401) has achieved preclinical proof of concept, showing anti-fibrotic activity in mouse models[1]. Its oncology program (CT-1119) reached IND-enabling/preclinical stage, planning a Phase 1 trial in China before operations were paused[1]. The Moderna collaboration yielded robust preclinical anti-tumor activity for CAR-M therapies targeting glypican-3, with 12 targets nominated, but Carisma will no longer conduct further R&D on this partnership[1].
- Therapeutic areas
- OncologyGastroenterology
- Modalities
- Cell therapyCAR-macrophage therapyCAR-monocyte therapymRNA-based drugsLipid nanoparticle delivery therapy
- Industry
- Biotech
Drug pipeline
21 assets20 more assets in the full pipeline.
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