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Carmine Therapeutics is a biotechnology company pioneering a new class of non-viral gene therapies based on red blood cell-derived extracellular vesicles (RBCEVs). Utilizing its proprietary REGENT platform, the company develops therapies capable of delivering large genetic payloads, such as mRNA and large DNA constructs, which are often too large for traditional viral vectors. The RBCEV approach offers advantages in safety, low immunogenicity, and the ability for repeat administration, addressing key hurdles in current gene therapy. Carmine has entered into a major strategic collaboration with Takeda to discover and develop gene therapies for rare diseases. The company operates out of Cambridge, Massachusetts, and Singapore, supported by a founding team of world-renowned experts in hematology and extracellular vesicle biology.
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