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Cartherics

Melbourne/Notting Hill, Victoria, Australiacartherics.com ↗

Ownership: Private
Employees: ~45
Development stage: Other

Overview

Cartherics has demonstrated strong preclinical results with its lead product CTH‑401—an iPSC-derived CAR-NK cell targeting TAG‑72—showing effective killing of ovarian cancer cells in vitro and in animal models. The company plans to initiate its first clinical trial for this program in the near future. Its pipeline includes additional programs targeting other solid tumors and diseases such as endometriosis and Alzheimer’s disease. The company recently raised over AU$15 million to support these efforts.

Therapeutic areas: OncologyNeurologyWomen's Health
Modalities: Allogeneic (off-the-shelf) CAR-NK cellsAllogeneic CAR-T cellsAutologous CAR-T cellsExtracellular vesicles (EVs/exosomes)Gene-edited iPSC-derived immune cells (NK, T, macrophages)
Industry: Biotech

Drug pipeline

16 assets

CTH-401

Preclinical

15 more assets in the full pipeline.

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Partnerships

ToolGen (gene-editing tools)Ohio State University & TiCARos (collaborations on TF-CAR technology)various academic institutions for research partnerships

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