Company intelligence / Profile preview
Cascade Prodrug, Inc.
Hillsboro, Oregon, United Statescascadeprodrug.com ↗
- Ownership
- Private
- Development stage
- Preclinical
01
Overview
Lead candidate CPD100Li has demonstrated strong preclinical activity in hypoxic solid tumor models. The compound selectively activates under low oxygen conditions typical of solid tumors and converts to cytotoxic vinblastine only within the tumor microenvironment. Preclinical data show a significant increase in susceptibility of tumor cells to CPD100Li under hypoxic conditions. The company received FDA Orphan Drug Designation for CPD100Li for pancreatic cancer but has not yet entered clinical trials.[6][7]
- Therapeutic areas
- Oncology
- Modalities
- Small molecules (specifically hypoxia-activated prodrugs; N-oxide prodrug of vinblastine)
- Industry
- Biotech
02
Drug pipeline
3 assets2 more assets in the full pipeline.
03
Partnerships
Oregon State University collaboration on preclinical research for pancreatic cancer therapy development[6]
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