Company intelligence / Profile preview

Celldex Therapeutics

Hampton, New Jersey, USAcelldex.com ↗
Ownership
Public · CLDX
Employees
~186
Development stage
Phase 3
01

Overview

Celldex’s lead asset, barzolvolimab—a monoclonal antibody targeting the KIT receptor—has advanced to Phase 3 trials for chronic spontaneous urticaria and completed or ongoing Phase 2 studies in other mast cell-driven diseases. The company is also developing bispecific antibodies such as CDX‑622 and CDX‑585 for inflammatory diseases and oncology. Previous programs in oncology were discontinued after mixed results; current focus is on severe allergic/inflammatory conditions with significant unmet need.[5][6][10]

Therapeutic areas
GastroenterologyDermatology
Modalities
Monoclonal antibodies (mAbs)Bispecific antibodies[1][2][4][5]
Industry
Biotech
02

Drug pipeline

28 assets

barzolvolimab

3

27 more assets in the full pipeline.

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03

Partnerships

Past collaborations with Medarex, Inc.Strategic partnerships with academic institutions and research organizations noted historically but no major current pharma partners listed in recent disclosures.[3][4]
04

Financials

Market cap
$2.6B
Total revenue
$22K
Enterprise value
$1.9B

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