Company intelligence / Profile preview

Celyad Oncology

Mont-Saint-Guilbert, Wallonia, Belgiumcelyad.com ↗
Ownership
Private
Employees
~19
Development stage
Phase 1
01

Overview

Until late 2022, Celyad Oncology was a clinical-stage biotech with several early-phase trials in allogeneic and autologous CAR-T therapies. Its lead programs included CYAD‑101 for metastatic colorectal cancer and CYAD‑211 for multiple myeloma. Both were discontinued after limited efficacy signals but proof-of-concept safety data for the shRNA platform. The company now focuses on research, technology development, and licensing its intellectual property estate.

Therapeutic areas
Oncology
Modalities
Chimeric Antigen Receptor T-cells (CAR-T)Allogeneic CAR-T (off-the-shelf)Autologous CAR-T (personalized)shRNA-based cell therapy
Industry
Biotech
02

Drug pipeline

18 assets

C-Cure

3

17 more assets in the full pipeline.

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03

Partnerships

MSD/Merck & Co., Inc.: Clinical trial collaboration on KEYNOTE-B79 trial with pembrolizumab + CYAD–101 in mCRC patientsNovartis International AG – Licensing agreement related to US patents on allogenic CAR–T cells.Horizon Discovery/PerkinElmer – Collaboration/license agreements regarding use of shRNA reagents.

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