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The Centro Oncológico de Excelencia (COE) is a specialized healthcare and clinical research institution based in Argentina, renowned for its historical contributions to oncology and bioethics. Founded in 1986 by the pioneering surgeon Dr. José María Mainetti in Gonnet, La Plata, the center was established as a hub for cancer diagnosis, treatment, and medical education. While the original facility underwent a period of transition, the COE brand remains a vital part of the Argentine clinical research landscape, with active sites in San Juan and Buenos Aires. The institution serves as a key partner for global pharmaceutical companies, including Pfizer, Roche, and BioNTech, hosting Phase II and III clinical trials for advanced therapies such as antibody-drug conjugates and targeted small molecules. Its legacy includes the establishment of the first School of Oncology in the region and a significant focus on humanistic medical care.
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