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Cephalix (now operating as Man & Science) is a Belgian medical technology company specializing in innovative neuromodulation solutions for chronic headache disorders. The company is developing a minimally invasive, battery-free implantable neurostimulation system designed to target the occipital nerves for the treatment of chronic cluster headaches and migraines. In 2021, its Occipital Nerve Field Stimulation System (ONFS) received FDA Breakthrough Device Designation for chronic cluster headache. Man & Science further expanded its portfolio in 2022 by acquiring Palion Medical, adding precision-navigated injectable therapy solutions to its pipeline. The company's technology platform is shared with its sister company, Nyxoah, which focuses on sleep apnea applications.
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