Cerule International

Cerule is a private U.S.-based wellness and nutraceutical company that markets science-positioned dietary supplements, skincare products, and related functional wellness products through a direct-selling and affiliate model. The company emphasizes patented ingredients and clinical-study support, with flagship products including StemEnhance ULTRA, PlasmaFlo, Cyactiv, and Cyactiv Joint. Its product positioning centers on stem cell support, circulation support, inflammation and mobility support, and skin rejuvenation rather than development of prescription therapeutics. Cerule describes itself as a biotech company, but operationally it appears closer to a commercial nutraceutical and wellness products business than a traditional drug-development biotech. The company sells internationally and is headquartered in Irvine, California.