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Chase Pharmaceuticals is a clinical-stage biopharmaceutical company focused on developing improved treatments for neurodegenerative disorders, specifically Alzheimer's disease. The company's lead candidate, CPC-201, is a combination of the acetylcholinesterase inhibitor donepezil and the peripherally acting muscarinic antagonist solifenacin. This approach aims to allow for higher, more effective doses of donepezil by mitigating its dose-limiting gastrointestinal side effects. Chase was acquired by Allergan in 2016 to bolster its central nervous system (CNS) pipeline. The acquisition was valued at up to $1 billion, including an upfront payment and potential regulatory and sales milestones. The company's founders subsequently launched Chase Therapeutics to focus on other neurological indications.
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