Chemical Probes Portal

The Chemical Probes Portal is an active non-profit online resource founded in 2015 that supports life science researchers globally by providing expert-reviewed evaluations and recommendations on small-molecule chemical probes used as tools for target validation and mechanistic studies across diverse disease areas such as cancer and neurodegeneration. It does not develop drugs or run clinical programs itself but curates data on hundreds of compounds—including inhibitors, agonists/antagonists/degraders like PROTACs—and covers more than 600 protein targets through contributions from leading scientists worldwide. Closely associated with major academic centers like the Institute of Cancer Research London and others internationally, it serves as an authoritative guide to best practices for probe selection/use rather than functioning as a traditional biotech/pharma company.