ChromaTan

ChromaTan has commercialized the first-ever column-free, single-use steady-state continuous chromatography system based on Real Moving Bed technology. Their Kascade™ BioRMB™ and CCTC™ platforms enable dramatic improvements in recovery and productivity for biomanufacturing—especially for gene therapy products, mRNA-based drugs, monoclonal antibodies and fusion proteins—by eliminating columns and reducing resin consumption by up to 90%. The system offers enhanced purity profiles and operational savings. Pilot installations are ongoing with major biopharma companies targeting next-generation biologic modalities. The next value inflection point will be adoption into clinical manufacturing expected in Q2 2026.