City of Hope National Medical Center

City of Hope is a world-renowned independent biomedical research and treatment center for cancer, diabetes, and other life-threatening diseases. Founded in 1913 and headquartered in Duarte, California, it is a National Cancer Institute-designated comprehensive cancer center and a founding member of the National Comprehensive Cancer Network. The institution is a pioneer in bone marrow transplantation and immunotherapy, having played a critical role in the development of synthetic human insulin and several breakthrough cancer drugs like Herceptin and Rituxan. City of Hope operates its own on-site GMP manufacturing facilities, allowing it to rapidly transition laboratory discoveries into first-in-human clinical trials. Its integrated model combines advanced clinical care with a robust internal drug development pipeline, particularly in the field of CAR-T cell therapies.