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Climb Bio is a clinical-stage biotechnology company dedicated to developing precision therapies for rare childhood-onset epilepsies. The company utilizes a proprietary zebrafish-based phenotypic screening platform to identify small molecules that modulate serotonin signaling to reduce seizure activity. Its lead candidate, EPX-100 (clemizole hydrochloride), is currently in Phase 2 clinical trials for the treatment of Dravet syndrome. By repurposing and optimizing existing compounds, Climb Bio aims to provide safer and more effective treatment options for patients with severe, treatment-resistant seizure disorders.
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